This blog highlights the best 12 AI startups in the United States of America to watch in 2025, covering expertise, fundings, disruptive technologies, and significant growth potential. Whether you’re an investor, a tech enthusiast, or just curious about what’s next in AI, this list is your go-to guide for discovering the most promising startups this year. Let’s dive in! 🚀
Additionally, the list is limited to startups founded within the last seven years, reflecting the most recent and innovative entrants to this new world driven by AI.
1. Anthropic
- 🗓️ Founded: 2021
- 📍 Location: San Francisco, CA, USA
- 🏢 What they do: Develops advanced AI systems and models.
- 💰 Funding: $14.1B
Anthropic is a leading AI safety and research company aiming to create AI systems that are aligned with human values. Known for its work on language models, Anthropic has gained significant traction for prioritising ethical AI development.
2. Abridge
- 🗓️ Founded: 2018
- 📍 Location: Pittsburgh, PA, USA
- 🏢 What they do: Simplifies medical conversations using AI-powered transcription and summarisation.
- 💰 Funding: $213M
Abridge transforms how healthcare professionals and patients communicate by providing accurate summaries of medical discussions. Its AI technology helps bridge gaps in understanding and improves patient outcomes.
3. Insitro
- 🗓️ Founded: 2018
- 📍 Location: South San Francisco, CA, USA
- 🏢 What they do: Combines AI and biology for drug discovery and development.
- 💰 Funding: $643M
Insitro leverages machine learning to accelerate the drug discovery process, making it faster and more efficient. With partnerships in the pharmaceutical industry, it’s transforming the way medicines are developed.
4. Anyscale
- 🗓️ Founded: 2019
- 📍 Location: San Francisco, CA, USA
- 🏢 What they do: Builds scalable AI infrastructure using Ray, an open-source framework.
- 💰 Funding: $260M
Anyscale empowers developers to deploy and scale AI applications effortlessly. By simplifying distributed computing, it’s paving the way for more accessible and robust AI infrastructure.
5. Glean
- 🗓️ Founded: 2019
- 📍 Location: Palo Alto, CA, USA
- 🏢 What they do: Enhances workplace productivity through AI-powered search and knowledge hub.
- 💰 Funding: $360M
Glean uses AI to unify workplace information, allowing employees to quickly find documents, emails, and files. It’s revolutionising how organisations manage and access their knowledge.
6. Cleanlab
- 🗓️ Founded: 2020
- 📍 Location: Cambridge, MA, USA
- 🏢 What they do: Detects and fixes data quality issues for machine learning applications.
- 💰 Funding: $30M
Cleanlab ensures the reliability of machine learning datasets by identifying and addressing data errors. This improves the performance of AI models and enhances trust in AI systems.
7. Codeium
- 🗓️ Founded: 2021
- 📍 Location: New York, NY, USA
- 🏢 What they do: Provides AI-powered code generation and developer tools
- 💰 Funding: $240M
Codeium is transforming software development with AI-assisted coding tools that boost developer productivity. Its technology helps coders write better, faster, and more efficient code.
8. Adept AI
- 🗓️ Founded: 2022
- 📍 Location: San Francisco, CA, USA
- 🏢 What they do: Develops AI models that can learn to use software tools autonomously.
- 💰 Funding: $415M
Adept’s innovative approach enables AI systems to autonomously perform tasks using existing software. This has significant potential to transform productivity across industries.
9. Together AI
- 🗓️ Founded: 2021
- 📍 Location: Palo Alto, CA, USA
- 🏢 What they do: Builds open and decentralised AI models for collaborative development.
- 💰 Funding: $229M
Together AI fosters an open ecosystem for building and sharing AI models. Its mission is to make AI development collaborative, transparent, and accessible to all.
10. Replit
- 🗓️ Founded: 2020
- 📍 Location: San Francisco, California
- 🏢 What they do: Develops AI-powered tools for automating and optimising software development workflows.
- 💰 Funding: $1M
Replit is a collaborative browser-based IDE that leverages AI to enhance coding productivity. It offers features like real-time code completion, debugging assistance, and AI-powered code generation. Replit also includes Ghostwriter, an AI tool that helps developers write code faster by providing intelligent suggestions and automating repetitive tasks.
Replit has gained significant traction among developers, students, and educators, making it a standout in the AI-driven coding space.
11. MindsDB
- 🗓️ Founded: 2017
- 📍 Location: Berkeley, CA, USA
- 🏢 What they do: Simplifies machine learning deployment by enabling ML models directly in databases.
- 💰 Funding: $41.5M
MindsDB integrates AI into databases, enabling businesses to gain predictive insights from their data. It’s empowering developers to use machine learning without extensive expertise.
12. Labelbox
- 🗓️ Founded: 2018
- 📍 Location: San Francisco, CA, USA
- 🏢 What they do: Provides tools to label, manage, and optimise AI training data.
- 💰 Funding: $189M
Labelbox simplifies the process of creating high-quality datasets for machine learning. Its platform accelerates AI training by providing intuitive data labelling and management tools.
References
- Forbes' AI 50 2024
- Exploding Topic's 60 Growing AI Companies & Startups 2024
- Notice.co (for private stock charts)
- AI Predictions